Compile Data Set for Download or QSAR
Found 62 of ic50 data for polymerid = 7986
TargetHistone-lysine N-methyltransferase EZH2 [A677G](Homo sapiens (Human))
Epizyme, Inc.

US Patent
LigandPNGBDBM172176(EPZ009161 | US10155002, Compound 184 | US11052093,...)copy SMILEScopy InChI
Affinity DataIC50: 0.800nMAssay Description:Test compounds were serially diluted 3-fold in DMSO in a 10 point-curve and 1 uL was spotted into a 384-well microplate in duplicate using a Platemat...More data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2ZW1JQPUS Patent
TargetHistone-lysine N-methyltransferase EZH2 [A677G](Homo sapiens (Human))
Epizyme, Inc.

US Patent
LigandPNGBDBM190202(EPZ008337 | US9175331, 32)copy SMILEScopy InChI
Affinity DataIC50: 0.800nMAssay Description:Test compounds were serially diluted 3-fold in DMSO in a 10 point-curve and 1 uL was spotted into a 384-well microplate in duplicate using a Platemat...More data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2ZW1JQPUS Patent
TargetHistone-lysine N-methyltransferase EZH2 [A677G](Homo sapiens (Human))
Epizyme, Inc.

US Patent
LigandPNGBDBM190201(EPZ008336 | US9175331, 31)copy SMILES
Affinity DataIC50: 1.30nMAssay Description:Test compounds were serially diluted 3-fold in DMSO in a 10 point-curve and 1 uL was spotted into a 384-well microplate in duplicate using a Platemat...More data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2ZW1JQPUS Patent
TargetHistone-lysine N-methyltransferase EZH2 [A677G](Homo sapiens (Human))
Epizyme, Inc.

US Patent
LigandPNGBDBM190200(EPZ008335 | US9175331, 30)copy SMILES
Affinity DataIC50: 1.5nMAssay Description:Test compounds were serially diluted 3-fold in DMSO in a 10 point-curve and 1 uL was spotted into a 384-well microplate in duplicate using a Platemat...More data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2ZW1JQPUS Patent
TargetHistone-lysine N-methyltransferase EZH2 [A677G](Homo sapiens (Human))
Epizyme, Inc.

US Patent
LigandPNGBDBM190199(EPZ008286 | US9175331, 29)copy SMILES
Affinity DataIC50: 1.5nMAssay Description:Test compounds were serially diluted 3-fold in DMSO in a 10 point-curve and 1 uL was spotted into a 384-well microplate in duplicate using a Platemat...More data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2ZW1JQPUS Patent
TargetHistone-lysine N-methyltransferase EZH2 [A677G](Homo sapiens (Human))
Epizyme, Inc.

US Patent
LigandPNGBDBM190203(EPZ008344 | US9175331, 34)copy SMILES
Affinity DataIC50: 1.60nMAssay Description:Test compounds were serially diluted 3-fold in DMSO in a 10 point-curve and 1 uL was spotted into a 384-well microplate in duplicate using a Platemat...More data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2ZW1JQPUS Patent
TargetHistone-lysine N-methyltransferase EZH2 [A677G](Homo sapiens (Human))
Epizyme, Inc.

US Patent
LigandPNGBDBM190211(EPZ008990 | US9175331, 47)copy SMILES
Affinity DataIC50: 1.60nMAssay Description:Test compounds were serially diluted 3-fold in DMSO in a 10 point-curve and 1 uL was spotted into a 384-well microplate in duplicate using a Platemat...More data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2ZW1JQPUS Patent
TargetHistone-lysine N-methyltransferase EZH2 [A677G](Homo sapiens (Human))
Epizyme, Inc.

US Patent
LigandPNGBDBM172138(EPZ007428 | US10155002, Compound 145 | US11052093,...)copy SMILES
Affinity DataIC50: 1.90nMAssay Description:Test compounds were serially diluted 3-fold in DMSO in a 10 point-curve and 1 uL was spotted into a 384-well microplate in duplicate using a Platemat...More data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2ZW1JQPUS Patent
TargetHistone-lysine N-methyltransferase EZH2 [A677G](Homo sapiens (Human))
Epizyme, Inc.

US Patent
LigandPNGBDBM190198(EPZ008279 | US9175331, 27)copy SMILEScopy InChI
Affinity DataIC50: 2.20nMAssay Description:Test compounds were serially diluted 3-fold in DMSO in a 10 point-curve and 1 uL was spotted into a 384-well microplate in duplicate using a Platemat...More data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2ZW1JQPUS Patent
TargetHistone-lysine N-methyltransferase EZH2 [A677G](Homo sapiens (Human))
Epizyme, Inc.

US Patent
LigandPNGBDBM190210(EPZ008989 | US9175331, 46)copy SMILES
Affinity DataIC50: 2.20nMAssay Description:Test compounds were serially diluted 3-fold in DMSO in a 10 point-curve and 1 uL was spotted into a 384-well microplate in duplicate using a Platemat...More data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2ZW1JQPUS Patent
TargetHistone-lysine N-methyltransferase EZH2 [A677G](Homo sapiens (Human))
Epizyme, Inc.

US Patent
LigandPNGBDBM190183(EPZ006438 | US11052093, Compound 139 | US9175331, ...)copy SMILEScopy InChI
Affinity DataIC50: 2.20nMAssay Description:Test compounds were serially diluted 3-fold in DMSO in a 10 point-curve and 1 uL was spotted into a 384-well microplate in duplicate using a Platemat...More data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2ZW1JQPUS Patent
TargetHistone-lysine N-methyltransferase EZH2 [A677G](Homo sapiens (Human))
Epizyme, Inc.

US Patent
LigandPNGBDBM190196(EPZ008277 | US9175331, 25)copy SMILEScopy InChI
Affinity DataIC50: 2.30nMAssay Description:Test compounds were serially diluted 3-fold in DMSO in a 10 point-curve and 1 uL was spotted into a 384-well microplate in duplicate using a Platemat...More data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2ZW1JQPUS Patent
TargetHistone-lysine N-methyltransferase EZH2 [A677G](Homo sapiens (Human))
Epizyme, Inc.

US Patent
LigandPNGBDBM190223(EPZ009158 | US9175331, 60)copy SMILEScopy InChI
Affinity DataIC50: 2.70nMAssay Description:Test compounds were serially diluted 3-fold in DMSO in a 10 point-curve and 1 uL was spotted into a 384-well microplate in duplicate using a Platemat...More data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2ZW1JQPUS Patent
TargetHistone-lysine N-methyltransferase EZH2 [A677G](Homo sapiens (Human))
Epizyme, Inc.

US Patent
LigandPNGBDBM172174(EPZ008681 | US10155002, Compound 182 | US11052093,...)copy SMILES
Affinity DataIC50: 2.70nMAssay Description:Test compounds were serially diluted 3-fold in DMSO in a 10 point-curve and 1 uL was spotted into a 384-well microplate in duplicate using a Platemat...More data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2ZW1JQPUS Patent
TargetHistone-lysine N-methyltransferase EZH2 [A677G](Homo sapiens (Human))
Epizyme, Inc.

US Patent
LigandPNGBDBM172166(EPZ008280 | US10155002, Compound 174 | US11052093,...)copy SMILES
Affinity DataIC50: 2.80nMAssay Description:Test compounds were serially diluted 3-fold in DMSO in a 10 point-curve and 1 uL was spotted into a 384-well microplate in duplicate using a Platemat...More data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2ZW1JQPUS Patent
TargetHistone-lysine N-methyltransferase EZH2 [A677G](Homo sapiens (Human))
Epizyme, Inc.

US Patent
LigandPNGBDBM190206(EPZ008494 | US9175331, 37)copy SMILES
Affinity DataIC50: 2.80nMAssay Description:Test compounds were serially diluted 3-fold in DMSO in a 10 point-curve and 1 uL was spotted into a 384-well microplate in duplicate using a Platemat...More data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2ZW1JQPUS Patent
TargetHistone-lysine N-methyltransferase EZH2 [A677G](Homo sapiens (Human))
Epizyme, Inc.

US Patent
LigandPNGBDBM190217(EPZ009152 | US9175331, 54)copy SMILES
Affinity DataIC50: 2.90nMAssay Description:Test compounds were serially diluted 3-fold in DMSO in a 10 point-curve and 1 uL was spotted into a 384-well microplate in duplicate using a Platemat...More data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2ZW1JQPUS Patent
TargetHistone-lysine N-methyltransferase EZH2 [A677G](Homo sapiens (Human))
Epizyme, Inc.

US Patent
LigandPNGBDBM190204(EPZ008491 | US9175331, 35)copy SMILES
Affinity DataIC50: 2.90nMAssay Description:Test compounds were serially diluted 3-fold in DMSO in a 10 point-curve and 1 uL was spotted into a 384-well microplate in duplicate using a Platemat...More data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2ZW1JQPUS Patent
TargetHistone-lysine N-methyltransferase EZH2 [A677G](Homo sapiens (Human))
Epizyme, Inc.

US Patent
LigandPNGBDBM172167(EPZ008338 | US10155002, Compound 175 | US11052093,...)copy SMILES
Affinity DataIC50: 3.10nMAssay Description:Test compounds were serially diluted 3-fold in DMSO in a 10 point-curve and 1 uL was spotted into a 384-well microplate in duplicate using a Platemat...More data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2ZW1JQPUS Patent
TargetHistone-lysine N-methyltransferase EZH2 [A677G](Homo sapiens (Human))
Epizyme, Inc.

US Patent
LigandPNGBDBM190188(EPZ007426 | US9175331, 15)copy SMILES
Affinity DataIC50: 3.40nMAssay Description:Test compounds were serially diluted 3-fold in DMSO in a 10 point-curve and 1 uL was spotted into a 384-well microplate in duplicate using a Platemat...More data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2ZW1JQPUS Patent
TargetHistone-lysine N-methyltransferase EZH2 [A677G](Homo sapiens (Human))
Epizyme, Inc.

US Patent
LigandPNGBDBM190208(EPZ008630 | US9175331, 43)copy SMILES
Affinity DataIC50: 3.5nMAssay Description:Test compounds were serially diluted 3-fold in DMSO in a 10 point-curve and 1 uL was spotted into a 384-well microplate in duplicate using a Platemat...More data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2ZW1JQPUS Patent
TargetHistone-lysine N-methyltransferase EZH2 [A677G](Homo sapiens (Human))
Epizyme, Inc.

US Patent
LigandPNGBDBM172170(EPZ008592 | US10155002, Compound 178 | US11052093,...)copy SMILEScopy InChI
Affinity DataIC50: 3.5nMAssay Description:Test compounds were serially diluted 3-fold in DMSO in a 10 point-curve and 1 uL was spotted into a 384-well microplate in duplicate using a Platemat...More data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2ZW1JQPUS Patent
TargetHistone-lysine N-methyltransferase EZH2 [A677G](Homo sapiens (Human))
Epizyme, Inc.

US Patent
LigandPNGBDBM172135(EPZ007210 | US10155002, Compound 141 | US11052093,...)copy SMILES
Affinity DataIC50: 3.80nMAssay Description:Test compounds were serially diluted 3-fold in DMSO in a 10 point-curve and 1 uL was spotted into a 384-well microplate in duplicate using a Platemat...More data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2ZW1JQPUS Patent
TargetHistone-lysine N-methyltransferase EZH2 [A677G](Homo sapiens (Human))
Epizyme, Inc.

US Patent
LigandPNGBDBM190184(EPZ006632 | US9175331, 10)copy SMILEScopy InChI
Affinity DataIC50: 4nMAssay Description:Test compounds were serially diluted 3-fold in DMSO in a 10 point-curve and 1 uL was spotted into a 384-well microplate in duplicate using a Platemat...More data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2ZW1JQPUS Patent
TargetHistone-lysine N-methyltransferase EZH2 [A677G](Homo sapiens (Human))
Epizyme, Inc.

US Patent
LigandPNGBDBM190207(EPZ008496 | US9175331, 39)copy SMILES
Affinity DataIC50: 4nMAssay Description:Test compounds were serially diluted 3-fold in DMSO in a 10 point-curve and 1 uL was spotted into a 384-well microplate in duplicate using a Platemat...More data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2ZW1JQPUS Patent
TargetHistone-lysine N-methyltransferase EZH2 [A677G](Homo sapiens (Human))
Epizyme, Inc.

US Patent
LigandPNGBDBM190189(EPZ007478 | US9175331, 17)copy SMILES
Affinity DataIC50: 4.20nMAssay Description:Test compounds were serially diluted 3-fold in DMSO in a 10 point-curve and 1 uL was spotted into a 384-well microplate in duplicate using a Platemat...More data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2ZW1JQPUS Patent
TargetHistone-lysine N-methyltransferase EZH2 [A677G](Homo sapiens (Human))
Epizyme, Inc.

US Patent
LigandPNGBDBM190209(EPZ008686 | US9175331, 45)copy SMILES
Affinity DataIC50: 4.5nMAssay Description:Test compounds were serially diluted 3-fold in DMSO in a 10 point-curve and 1 uL was spotted into a 384-well microplate in duplicate using a Platemat...More data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2ZW1JQPUS Patent
TargetHistone-lysine N-methyltransferase EZH2 [A677G](Homo sapiens (Human))
Epizyme, Inc.

US Patent
LigandPNGBDBM172175(EPZ009097 | US10155002, Compound 183 | US11052093,...)copy SMILEScopy InChI
Affinity DataIC50: 4.60nMAssay Description:Test compounds were serially diluted 3-fold in DMSO in a 10 point-curve and 1 uL was spotted into a 384-well microplate in duplicate using a Platemat...More data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2ZW1JQPUS Patent
TargetHistone-lysine N-methyltransferase EZH2 [A677G](Homo sapiens (Human))
Epizyme, Inc.

US Patent
LigandPNGBDBM190194(EPZ007789 | US9175331, 22)copy SMILES
Affinity DataIC50: 4.80nMAssay Description:Test compounds were serially diluted 3-fold in DMSO in a 10 point-curve and 1 uL was spotted into a 384-well microplate in duplicate using a Platemat...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2ZW1JQPUS Patent
TargetHistone-lysine N-methyltransferase EZH2 [A677G](Homo sapiens (Human))
Epizyme, Inc.

US Patent
LigandPNGBDBM190221(EPZ009156 | US9175331, 58)copy SMILES
Affinity DataIC50: 5.10nMAssay Description:Test compounds were serially diluted 3-fold in DMSO in a 10 point-curve and 1 uL was spotted into a 384-well microplate in duplicate using a Platemat...More data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2ZW1JQPUS Patent
TargetHistone-lysine N-methyltransferase EZH2 [A677G](Homo sapiens (Human))
Epizyme, Inc.

US Patent
LigandPNGBDBM190218(EPZ009153 | US9175331, 55)copy SMILES
Affinity DataIC50: 5.60nMAssay Description:Test compounds were serially diluted 3-fold in DMSO in a 10 point-curve and 1 uL was spotted into a 384-well microplate in duplicate using a Platemat...More data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2ZW1JQPUS Patent
TargetHistone-lysine N-methyltransferase EZH2 [A677G](Homo sapiens (Human))
Epizyme, Inc.

US Patent
LigandPNGBDBM190216(EPZ009099 | US9175331, 53)copy SMILEScopy InChI
Affinity DataIC50: 5.70nMAssay Description:Test compounds were serially diluted 3-fold in DMSO in a 10 point-curve and 1 uL was spotted into a 384-well microplate in duplicate using a Platemat...More data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2ZW1JQPUS Patent
TargetHistone-lysine N-methyltransferase EZH2 [A677G](Homo sapiens (Human))
Epizyme, Inc.

US Patent
LigandPNGBDBM190190(EPZ007648 | US9175331, 18)copy SMILES
Affinity DataIC50: 5.80nMAssay Description:Test compounds were serially diluted 3-fold in DMSO in a 10 point-curve and 1 uL was spotted into a 384-well microplate in duplicate using a Platemat...More data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2ZW1JQPUS Patent
TargetHistone-lysine N-methyltransferase EZH2 [A677G](Homo sapiens (Human))
Epizyme, Inc.

US Patent
LigandPNGBDBM190185(EPZ007038 | US9175331, 11)copy SMILES
Affinity DataIC50: 6nMAssay Description:Test compounds were serially diluted 3-fold in DMSO in a 10 point-curve and 1 uL was spotted into a 384-well microplate in duplicate using a Platemat...More data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2ZW1JQPUS Patent
TargetHistone-lysine N-methyltransferase EZH2 [A677G](Homo sapiens (Human))
Epizyme, Inc.

US Patent
LigandPNGBDBM172168(EPZ008495 | US10155002, Compound 176 | US11052093,...)copy SMILEScopy InChI
Affinity DataIC50: 6.30nMAssay Description:Test compounds were serially diluted 3-fold in DMSO in a 10 point-curve and 1 uL was spotted into a 384-well microplate in duplicate using a Platemat...More data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2ZW1JQPUS Patent
TargetHistone-lysine N-methyltransferase EZH2 [A677G](Homo sapiens (Human))
Epizyme, Inc.

US Patent
LigandPNGBDBM190195(EPZ007790 | US9175331, 23)copy SMILES
Affinity DataIC50: 7.30nMAssay Description:Test compounds were serially diluted 3-fold in DMSO in a 10 point-curve and 1 uL was spotted into a 384-well microplate in duplicate using a Platemat...More data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2ZW1JQPUS Patent
TargetHistone-lysine N-methyltransferase EZH2 [A677G](Homo sapiens (Human))
Epizyme, Inc.

US Patent
LigandPNGBDBM190186(EPZ007209 | US9175331, 12)copy SMILEScopy InChI
Affinity DataIC50: 8.60nMAssay Description:Test compounds were serially diluted 3-fold in DMSO in a 10 point-curve and 1 uL was spotted into a 384-well microplate in duplicate using a Platemat...More data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2ZW1JQPUS Patent
TargetHistone-lysine N-methyltransferase EZH2 [A677G](Homo sapiens (Human))
Epizyme, Inc.

US Patent
LigandPNGBDBM190197(EPZ008278 | US9175331, 26)copy SMILEScopy InChI
Affinity DataIC50: 9.30nMAssay Description:Test compounds were serially diluted 3-fold in DMSO in a 10 point-curve and 1 uL was spotted into a 384-well microplate in duplicate using a Platemat...More data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2ZW1JQPUS Patent
TargetHistone-lysine N-methyltransferase EZH2 [A677G](Homo sapiens (Human))
Epizyme, Inc.

US Patent
LigandPNGBDBM190212(EPZ008991 | US9175331, 48)copy SMILEScopy InChI
Affinity DataIC50: 9.40nMAssay Description:Test compounds were serially diluted 3-fold in DMSO in a 10 point-curve and 1 uL was spotted into a 384-well microplate in duplicate using a Platemat...More data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2ZW1JQPUS Patent
TargetHistone-lysine N-methyltransferase EZH2 [A677G](Homo sapiens (Human))
Epizyme, Inc.

US Patent
LigandPNGBDBM190191(EPZ007649 | US9175331, 19)copy SMILES
Affinity DataIC50: 9.60nMAssay Description:Test compounds were serially diluted 3-fold in DMSO in a 10 point-curve and 1 uL was spotted into a 384-well microplate in duplicate using a Platemat...More data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2ZW1JQPUS Patent
TargetHistone-lysine N-methyltransferase EZH2 [A677G](Homo sapiens (Human))
Epizyme, Inc.

US Patent
LigandPNGBDBM172165(EPZ008205 | US10155002, Compound 173 | US11052093,...)copy SMILEScopy InChI
Affinity DataIC50: 11.2nMAssay Description:Test compounds were serially diluted 3-fold in DMSO in a 10 point-curve and 1 uL was spotted into a 384-well microplate in duplicate using a Platemat...More data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2ZW1JQPUS Patent
TargetHistone-lysine N-methyltransferase EZH2 [A677G](Homo sapiens (Human))
Epizyme, Inc.

US Patent
LigandPNGBDBM50075051(CHEMBL3360855 | EPZ005687 | US10273223, Compound C...)copy SMILEScopy InChI
Affinity DataIC50: 11.3nMAssay Description:Test compounds were serially diluted 3-fold in DMSO in a 10 point-curve and 1 uL was spotted into a 384-well microplate in duplicate using a Platemat...More data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2ZW1JQPUS Patent
TargetHistone-lysine N-methyltransferase EZH2 [A677G](Homo sapiens (Human))
Epizyme, Inc.

US Patent
LigandPNGBDBM190193(EPZ007692 | US9175331, 21)copy SMILES
Affinity DataIC50: 11.6nMAssay Description:Test compounds were serially diluted 3-fold in DMSO in a 10 point-curve and 1 uL was spotted into a 384-well microplate in duplicate using a Platemat...More data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2ZW1JQPUS Patent
TargetHistone-lysine N-methyltransferase EZH2 [A677G](Homo sapiens (Human))
Epizyme, Inc.

US Patent
LigandPNGBDBM190215(EPZ009090 | US9175331, 51)copy SMILEScopy InChI
Affinity DataIC50: 12nMAssay Description:Test compounds were serially diluted 3-fold in DMSO in a 10 point-curve and 1 uL was spotted into a 384-well microplate in duplicate using a Platemat...More data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2ZW1JQPUS Patent
TargetHistone-lysine N-methyltransferase EZH2 [A677G](Homo sapiens (Human))
Epizyme, Inc.

US Patent
LigandPNGBDBM190214(EPZ008994 | US9175331, 50)copy SMILEScopy InChI
Affinity DataIC50: 12.1nMAssay Description:Test compounds were serially diluted 3-fold in DMSO in a 10 point-curve and 1 uL was spotted into a 384-well microplate in duplicate using a Platemat...More data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2ZW1JQPUS Patent
TargetHistone-lysine N-methyltransferase EZH2 [A677G](Homo sapiens (Human))
Epizyme, Inc.

US Patent
LigandPNGBDBM190187(EPZ007227 | US9175331, 14)copy SMILES
Affinity DataIC50: 12.2nMAssay Description:Test compounds were serially diluted 3-fold in DMSO in a 10 point-curve and 1 uL was spotted into a 384-well microplate in duplicate using a Platemat...More data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2ZW1JQPUS Patent
TargetHistone-lysine N-methyltransferase EZH2 [A677G](Homo sapiens (Human))
Epizyme, Inc.

US Patent
LigandPNGBDBM190205(EPZ008493 | US9175331, 36)copy SMILEScopy InChI
Affinity DataIC50: 12.7nMAssay Description:Test compounds were serially diluted 3-fold in DMSO in a 10 point-curve and 1 uL was spotted into a 384-well microplate in duplicate using a Platemat...More data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2ZW1JQPUS Patent
TargetHistone-lysine N-methyltransferase EZH2 [A677G](Homo sapiens (Human))
Epizyme, Inc.

US Patent
LigandPNGBDBM190219(EPZ009154 | US9175331, 56)copy SMILES
Affinity DataIC50: 14.1nMAssay Description:Test compounds were serially diluted 3-fold in DMSO in a 10 point-curve and 1 uL was spotted into a 384-well microplate in duplicate using a Platemat...More data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2ZW1JQPUS Patent
TargetHistone-lysine N-methyltransferase EZH2 [A677G](Homo sapiens (Human))
Epizyme, Inc.

US Patent
LigandPNGBDBM190224(EPZ009162 | US9175331, 62)copy SMILEScopy InChI
Affinity DataIC50: 14.6nMAssay Description:Test compounds were serially diluted 3-fold in DMSO in a 10 point-curve and 1 uL was spotted into a 384-well microplate in duplicate using a Platemat...More data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2ZW1JQPUS Patent
TargetHistone-lysine N-methyltransferase EZH2 [A677G](Homo sapiens (Human))
Epizyme, Inc.

US Patent
LigandPNGBDBM190182(EPZ006089 | US9175331, 8)copy SMILEScopy InChI
Affinity DataIC50: 19nMAssay Description:Test compounds were serially diluted 3-fold in DMSO in a 10 point-curve and 1 uL was spotted into a 384-well microplate in duplicate using a Platemat...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2ZW1JQPUS Patent
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